Interestingly, LIN28A is associated with specific ribosomal proteins in an RNA-independent mode, and several of these proteins, such as RPL5, RPL10, and RPS27L, have been shown to promote tumorigenesis or cancer (Aspesi and Ellis, 2019; Huang et al., 2013; Xiong et al., 2014). This evidence concerns the gene LIN28A and cancer.