Totally, we performed scRNA-seq on 165 tumor cells from four mammary tumors of distinct molecular subtypes (termed as BrT1, BrT2, Br53T1, and Br53T2; Table S5), as well as 312 luminal cells from female mice with three different genotypes (Brca1 mutant; Trp53 mutant; and Brca1/ Trp53 double mutant, Table S5). The gene discussed is TP53; the disease is breast cancer.