PROS1 and COVID-19: To date, the evidence about SARS-CoV-2 infecting BMVECs of the BBB are limited; only one autopsy study described the viral-associated proteins detected in BMVECs of the frontal lobe of a COVID-19 patient.16 This shows that SARS-CoV-2 infects BMVECs of the BBB, even though this infection from the brain or blood is unclear.