This finding is consistent with HB-EGF amelioration of oxidative stress-mediated uterine decidualization damage, downregulation of circulatory lipid levels, protection against atherosclerosis in the vascular wall, and attenuation of lung inflammation and injury in a murine model of pulmonary emphysema (Hai-Fan Yu et al. 2019,S Kim et al. 2019,Yanwei Suet al. 2019). Here, GSTM1 is linked to pulmonary emphysema.