MGMT and neoplasm: On the basis of molecular pathology diagnosis results, previous researches have suggested that the tumor markers such as IDH mutation status [2], MGMT promoter methylation [3] and TERT promoter mutation status [4] and so on are independently or interactively associated with the disease free survival and the overall survival in glioma patients, even affecting the operation and concurrent chemo-radiotherapy of glioma patients.