In forty-six glioma patients, the number of IDH mutated patients were 21 (45.7%), IDH wild-type were 25 (54.3%), TERT mutated were 29(63%), TERT wild-type were 17(37%), MGMT promotor methylation were 33(71.7%), MGMT promotor un-methylation were 13(28.3%) respectively. The gene discussed is MGMT; the disease is central nervous system cancer.