Then, we further evaluated the prognostic value of the rest complement genes, whose mRNA expressions were not altered in HCC tissues, including C1S, C2, C3, C5, C8A, C8B, C8G, CFB, CFI, CFH, CFHR1, CFHR2, CFHR4, CFHR5, SERPING1, MASP1, MASP2, MBL2, C5AR2, C4BPA, C4BPB, VTN, CLU, CD59, CPN1, CR2, and ITGAM. Here, C3 is linked to hepatocellular carcinoma.