Furthermore, we conducted KEGG analysis (Figure 6D,E), 19 pathways including hsa 03320: PPAR signaling pathway, hsa 04064: NF‐kappa B signaling pathway, and hsa 04151: PI3K‐Akt signaling pathway, were associated with overexpression of the five complement genes, while nine pathways including KO 03460: Fanconi anemia pathway, KO 05206: MicroRNAs in cancer, and KO 04115: P53 signaling pathway were associated with down‐expression of these genes. This evidence concerns the gene TP53 and cancer.