Apart from complement genes mentioned above, the mRNA expressions of C2, CFH, CFHR1, CFHR2, CFHR4, SERPING1, MASP2, MASP1, C4BPB, VTN, CPN1, and CR2 were associated with OS, DFS, and PFS in patients with HCC. The gene discussed is C4BPB; the disease is hepatocellular carcinoma.