According to our results shown in Tables 4 and 5, we found that lower expressions of C1S, C2, C3, C5, C8B, CFB, CFI, CFH, CFHR1, CFHR2, CFHR4, SERPING1, MASP2, MASP1, MBL2, C4BPA, C4BPB, VTN, CLU, CPN1, and CR2 were associated with shorter DFS and PFS in patients with HCC. The gene discussed is CFB; the disease is hepatocellular carcinoma.