Apart from complement genes mentioned above, the mRNA expressions of C2, CFH, CFHR1, CFHR2, CFHR4, SERPING1, MASP2, MASP1, C4BPB, VTN, CPN1, and CR2 were associated with OS, DFS, and PFS in patients with HCC. Here, CR2 is linked to hepatocellular carcinoma.