CNOT8 and dental caries: A case in point are colloidal CaF2, which were developed for upconversion fluorescence,8 time-resolved luminescent,9 antifungal coating,10in vivo magnetic resonance imaging (MRI),11−14 prodrug activation,15 photodynamic therapy,16 remineralization of dental caries,17 and in situ NMR studies.18 In allthese studies, the colloidal characteristics of the synthetic CaF2 NCs are of paramount importance to their desired propertiesand function.