However, CD11b antibody could not disturb the effect of rh‐sICAM‐1 in THP‐1 coculture on the invasion of GBM, indicating that interaction of sICAM‐1 with LFA‐1 is critical for induction of WNT3A in macrophages, whereas Mac‐1 is not involved in this event. Here, WNT3A is linked to glioblastoma.