Similarly, variants in ANK2 have been identified in individuals with ASD and intellectual disability (De Rubeis et al., 2014; Iossifov et al., 2014; Iossifov et al., 2015) and it is ranked as a top high confidence ASD gene with one of the highest mutability scores (Ruzzo et al., 2019). The gene discussed is ANK2; the disease is Intellectual disability.