CCL2 and breast cancer: Conditioned medium from human mammary cancer-associated adipocytes increased MCP-1 levels, which decreased vimentin expression in MDA-MB-231 cells [19]; this is in agreement with the increased concentration of MCP-1 in treatment-conditioned media and decreased vimentin protein expression observed in the Dox+CM-treated compared to the Dox-treated group in our current in vitro model.