ATG5 and Parkinson disease: Our study showed that conditional deletion of microglial Atg5 by crossing Atg5f/f with Lyz2Cre lines did not induce obvious neurodegeneration or motor coordination defects in mice up to 5 months old, but promoted the neurodegeneration in different PD mouse models, consistent with previous studies (Choi et al., 2020; H. J. Kim et al., 2017; Qin et al., 2021).