For example, the levels of hsv1-miR-H18 and hsv2-miR-H9-5p [31] and miR-148a and miR-375 [32] have been reported to be better predictors of the disease than serum PSA when comparing prostate cancer patients with healthy individuals and/or men with benign prostate hyperplasia (BPH). This evidence concerns the gene KLK3 and prostate carcinoma.