Although blocking Golgi export of FLT3 with monensin altered levels of pAKT, pERK, and STAT5, these effects were various among MOLM-14, MV4-11, and Kasumi-6 (Fig. 4e,f), and the persistence of this phosphorylation in the presence of monensin was common to all these AML cell lines. This evidence concerns the gene FLT3 and acute myeloid leukemia.