MUC1 and pneumonia: In fact, in a mouse model of Pa pneumonia, co-administration of the MUC1-ED decoy receptor with a lethal challenge of Pa diminished lung bacterial burden, lung cytokine production, and pulmonary leukostasis, and increased 5-day survival from 0 to 77%, indicating that the shed MUC1-ED constitutes a protective component of the host response to Pa22 (Fig. 1).