TGFB1 and neoplasm: Transcriptome signature analysis of cells modulated for Platr18, hnRNP E1, or treated with TGFβ (Fig 2B) revealed semaphorin-4F (Sema4F) as the most regulated transcript by Platr18 overexpression itself (Figs 2B and C and S2A) and one of the most modulated RNAs during tumor cell EMT in general (Fig 2B and D).