TGFB1 and neoplasm: Because Sema4F silencing in NMuMG-E1KD cells and blockade of TGFβ signaling in 4T1 cells does not impact tumor growth in vivo, it constitutes appropriate and unbiased model to validate the pro-neurogenic role of TGFβ in primary breast tumors (Figs 4I and 5D).