Using microarray analysis of RNA retrieved from wild type (WT) and SND1-knockdown breast cancer SCP28 cell lines, it was shown that SND1-knockdown is strongly correlated with downregulation of a panel of oncogenes and metastatic genes such as Angiopoietin-like 4 (ANGPTL4), Epiregulin (EREG) and Inhibitor of DNA Binding 1 (ID1) known for being implicated in chemoresistance. The gene discussed is ID1; the disease is breast cancer.