NEFL and HIV infectious disease: Immunofluorescence and metamorph quantification showed that compared to control (PBS and MVC) groups, HIV infection decreased NFL expression by 4.75-fold (Fig. 6a and b; P < 0.0001); and NFL levels in the HIV + MVC group were increased by 5-fold compared to the HIV group (Fig. 6a and b, P < 0.0001).