MT3 and familial pancreatic carcinoma: Studies have shown that MMP-1, MMP-2, MMP-7, MMP-9, membrane type 1-MMP (MT1-MMP), MT2-MMP, and MT3-MMP are overexpressed in pancreatic cancer tumors, while MMP-2, MMP-7, and MMP-9 have been identified as potential biomarkers of pancreatic cancer [51].