Moreover, the prognostic value of NEDD4L expression on EFS and OS was further confirmed in another two independent cohorts of CN-AML from GSE6891 (probe 212445_s_at: P = 0.019 and 0.005, respectively; probe 241396_at: P < 0.001 and 0.001, respectively) and GSE10358 (probe 212445_s_at: P = 0.316 and 0.076, respectively; probe 241396_at: P = 0.005 and 0.001, respectively) datasets (Fig. 4b, c). Here, NEDD4L is linked to acute myeloid leukemia.