Although no remarkably differences of OS and LFS were observed between low- and high- NEDD4L expression groups among total AML (P = 0.952 and 0.972, respectively, Additional file 2: Fig. S1), patients with low NEDD4L expression tended to have shorter OS and LFS time than those with high NEDD4L expression among CN-AML (P = 0.161 and 0.122, respectively, Additional file 2: Fig. S1). This evidence concerns the gene NEDD4L and acute myeloid leukemia.