GFAP and Ataxia: Ugt8 was also validated in this study because mice with deficits in ether lipids have subtle abnormalities in myelination (76), and Ugt8 knockout mice recapitulate many phenotypic characteristics shared with GFAPTg;Gfap+/R236H mice ranging from tremors, mild ataxia, and hindlimb mobility impairment (66).