Similar to GFAPTg;Gfap+/R236H mice, Ugt8-deficient mice form myelin that also appears ultrastructurally normal and exhibit similar phenotypes as the GFAPTg;Gfap+/R236H mice, including a generalized tremor, mild ataxia, and age-related hindlimb paralysis (66). Here, UGT8 is linked to cerebellar ataxia.