Therefore, to determine whether the elevation of FABP7 and downregulation of UGT8 also occurs in the human disorder, Western blotting was performed in AxD patient (n = 4) relative to control (n = 3) brain tissue homogenates (supplemental Table S4 has sample demographic information and normalized protein values for FABP7 and UGT8). The gene discussed is UGT8; the disease is Alexander disease.