Both PRSS36 and ZNF668 belong to the KRAB-ZFP cluster, which is involved with cell proliferation [49], hence aligns with impaired hippocampal neurogenesis being a potential mechanism underlying memory deficits in AD [50] and impaired precursor cell proliferation due to dopamine depletion in PD [51]. This evidence concerns the gene ZKSCAN7 and Alzheimer disease.