Several characteristics have been shown to confer an increased hypoglycaemia risk in patients with T2D, including older age,21 renal impairment,22, 23, 24 the presence of multiple comorbidities including diabetes comorbidities,25 and cardiovascular disease,26 long‐standing diabetes and/or insulin use, or the use of multiple daily injections or sulphonylureas.27 The gene discussed is INS; the disease is type 2 diabetes mellitus.