TCF7L2 and hepatocellular carcinoma: It is also a causative factor for the progression of hepatocellular carcinoma [35, 36], which might be ascribed to polymorphisms in TCF7L2 rs290487 and rs6585194 gene along with the presence of SNPs rs290481, rs290487, and rs29048 at 3′ end of TCF7L2 gene [37].