What is more, we only demonstrated the positive correlation between KIF4A and CDC5L by using TCGA data (GEPIA and GeneCards) and IHC (our clinical data), and we could say that KIF4A might promote pancreatic cancer proliferation by affecting the expression of CDC5L expression in the pathway, and further verification of this mechanism is needed in the future. Here, KIF4A is linked to familial pancreatic carcinoma.