For example, the prognosis in stable CAD was associated with myocardial stress and remodeling biomarkers like B-type natriuretic peptide (BNP), N-terminal pro-B-type natriuretic peptide (NT-proBNP), Mid-regional pro-A-type natriuretic peptide (MR-proANP), Mid-regional pro-adrenomedullin (MR-proADM), growth differentiation factor 15 (GDF-15), soluble suppression of tumorigenicity 2 (sST2), Renin, Copeptin and Pro-endothelin-1 (47). This evidence concerns the gene NPPB and coronary artery disorder.