TGFB1 and cancer: Additionally, higher levels of HOXA11-AS, HOTTIP, HOXB-AS3, HOXB-AS4, PRAC2, and HOXC13-AS were found to be associated with types 1, 2, and 6 infiltrates (i.e., C1, C2, and C6), indicating the tumor promoter role of these gene members, given that patients belonging to these categories, who showed a higher cancer cell proliferation rate as well as TGFβ enrichment, had lower survival rates (Lu et al., 2018).