INS and hyperlipidemia: In the in vivo experiment, the pumpkin polysaccharide treatment (PPS.H group, namely 1,200 mg/kg W-CCPs) significantly improved the symptoms of diabetic mice by lowering FBG and reducing insulin resistance, which is consistent with previous information that pumpkin or pumpkin polysaccharides had anti-hyperglycemic, anti-hyperlipidemia, and antioxidant effects (4, 8, 47, 48).