These studies should be corroborated by the genetic characterization of patients with COVID-19 by six nonsynonymous functional polymorphisms of TRPV-1 (K2N rs9894618, P91S rs222749, I315 M rs222747, T469I rs224534, T505A rs17633288, and I585V rs8065080), that determine a substantial difference in capsaicin sensitivity with levels of SNP-based responsiveness ranging from 2 to 6. Here, TRPV1 is linked to COVID-19.