Furthermore, research through the use of tailored doses and timing of administration, should confirm these data and mechanisms in order to develop medications, patch tests (capsaicin), nasal sprays, or food supplements based on TRPV-1 desensitization for the treatment of COVID-19 and its main symptoms, including not only cough but also pain and tachycardia. This evidence concerns the gene TRPV1 and COVID-19.