While, the PINK/PARKIN pathway has mostly been studied for its involvement in Parkinson disease and in mitochondrial quality control through mitophagy, several lines of evidence have proven that PINK/PARKIN activation has also prominent roles in driving mitochondrial dynamics by activating pro-fission and inactivating pro-fusion proteins, research that is described in detail in the recent review article (Ge et al., 2020). This evidence concerns the gene PRKN and Parkinson disease.