ERCC2 and neoplasm: Ravegnini et al. investigated the influence of polymorphisms in several DNA repair genes on GIST susceptibility and characteristics, and showed that XPD rs13181, hOGG1 rs1052133 and XPF rs1800067 were associated with GIST susceptibility, whereas XPA rs1800975 and rs2808668 were associated with tumor size, tumor metastasis and mitotic index (Ravegnini et al., 2016).