CD8A and melanoma: We quantified 22 major immune cells using CIBERSORT software and found that the main immune infiltration cells in melanoma are CD8 T cells and macrophages (Figures 6A,D and Supplementary Figures 7A–C), the low-risk group had higher CD8 T cell and macrophages M1 infiltration and lower macrophage M0/2 infiltration (Figure 6C).