Further supporting a role for DDR2 in tumor development, knockdown of the tumor invasion regulator N-Myc Downstream Regulated 1 (NDRG1) enhanced tumor cell adhesion, migration and invasion activities (without affecting cell proliferation) and significantly increasing DDR2 expression (in ovarian and cervical cell lines) (Zhao et al., 2011). This evidence concerns the gene DDR2 and neoplasm.