ARID1A and cancer: ARID1A is identified as a tumor suppressor gene and is mutated at a high frequency in diverse cancers (Wu and Roberts, 2013; Lo et al., 2021), such as ovarian clear cell carcinoma (∼57%), uterine corpus endometrial carcinoma (∼30%), and stomach adenocarcinoma (∼31%) (Lo et al., 2021).