DMD and Duchenne muscular dystrophy: HiPSC-CM generated via some of these methods have been used in the study of Duchenne muscular dystrophy (Long et al., 2018; Pioner et al., 2020), yet it has also been suggested that dystrophin is needed for hiPSC-CM maturation (Pioner et al., 2020), and presently it is unknown whether the DAPC in hiPSC-CM forms a complete functional complex.