BAX and preeclampsia: Studies have found that there is a decrease in proapoptotic proteins such as p53 and BCL2-associated X, and an increase in antiapoptotic protein such as B-cell lymphoma 2 (BCL2) in term preeclamptic syncytiotrophoblast mitochondria compared to the increase of BAX/BLC2 ratio preterm preeclampsia (Holland et al., 2017).