EGFR was overexpressed in multiple cancer types (Herbst and Shin, 2002), such as perihilar cholangiocarcinoma (Harder et al., 2009; Yang et al., 2014), and was affected by PDT using liposome bound ZnPc (Weijer et al., 2017). Here, EGFR is linked to hilar cholangiocarcinoma.