ICAM1 and Sepsis: Haileselassie et al. showed that vascular leukocyte adhesion factors such as vascular cell adhesion molecule-1(VCAM-1) and intercellular adhesion molecule-1(ICAM-1) increased in LPS model of sepsis after 24 hours’ treatment, indicating that inflammatory cells have adhered and transmigrated to vessels (Haileselassie et al., 2020) (Figure 1).