In this study, we found that upregulated MMP17 and MMP19 were significantly associated with a higher tumor stage (p = 4 × 10−4 and p = 2 × 10−3 for MMP17 and MMP19, respectively), a shorter OS time (HR = 1.24, p = 0.02 for MMP17 and HR = 1.92, p = 1.51 × 10−3 for MMP19), a shorter DSS time (HR = 1.41, p = 0.02 for MMP17 and HR = 1.9, p = 0.03 for MMP19), a shorter PFS (HR = 1.19, p = 0.04 for MMP17 and HR = 1.48, p = 0.03 for MMP19), and a shorter RFS (HR = 1.48, p = 3.01 × 10−3 for MMP17 and HR = 1.31, p = 2.35 × 10−5 for MMP19). Here, MMP17 is linked to neoplasm.