As shown in Figure 3, we found that MMP1, MMP3, MMP7, MMP9-MMP12, and MMP14 were significantly upregulated in tumor tissue, while MMP15–MMP17, MMP19–MMP21, MMP23A, MMP23B, and MMP25–MMP28 were significantly downregulated in tumor tissue. The gene discussed is MMP15; the disease is neoplasm.