For LUSC, the levels of BIRC5 expression correlated positively with tumor purity (Cor=0.336, P=4.47e-14), while BIRC5 expression was negatively correlated with CD4+T cells (Cor=-0.262, P=6.53e-09, macrophages (Cor=-0.289, P=1.16e-10), neutrophils (Cor=-0.137, P=2.83e-03), and dendritic cells (Cor=-0.218, P=1.68e-06); there was no significant association between B cells and CD8+T cells. The gene discussed is CD4; the disease is neoplasm.