In addition, we evaluated the prognostic roles of YTHDF1 and YTHDF3 in different molecular subtypes of breast cancer from HPA data and found that high expression of YTHDF1 was significantly related with poor prognosis in Her2 enriched and luminal B subtypes, while high expression of YTHDF3 was significantly correlated with poor prognosis in Her2 enriched, luminal A, and luminal B subtypes (Supplementary Figure S3). The gene discussed is YTHDF1; the disease is breast cancer.