Among them, the expression of RBM15, VIRMA, HNRNPA2B1, and YTHDF1/2/3 were significantly upregulated, but METTL3, METTL14, METTL16, WTAP, FTO, YTHDC1, and EIF3A had lower expression in breast cancer compared to normal samples (Figures 2A, B). This evidence concerns the gene METTL16 and breast carcinoma.