Data showed that the proportions of ER (r=−0.339, p=0.002) and PR (r=−0.247, p=0.011) were negatively correlated with the occurrence of extraaxillary lymph node metastasis (suspected and unsuspected), while diameter (r=0.3, p=0.008) and initial stage (r=0.455, p<0.001) were positively correlated with it, as presented in Table 2A. The gene discussed is ESR1; the disease is metastatic malignant neoplasm in the lymph nodes.