The result showed that the expression level of NLRP1, NOD1, PLCG1, PLCG1, GSDMB, NLRP6, GSDMC, NLRP7, IL1B, GSDMA, CASP3, NLRRC4MNLRP3, CASP8, CASP1, CASP4, CASP5, AIM2, NOD2, GPX4, GSDMD, PYCARD, and IL18 in the ccRCC tissues was higher than that in the normal renal tissues, while the expression level of genes containing CASP9 and NLRP2 in the normal renal tissues was higher than that in the ccRCC tissues (Figure 1A). The gene discussed is NOD2; the disease is nonpapillary renal cell carcinoma.