We found malignancies in 4/7 (57%) of 2-year-old Fancc-/-; Mad2+/- survivors, including one myeloproliferative disorder, one large Ki67+, cytokeratin-negative retroperitoneal solid tumor with gland-like structures, and one lymphoma (Supplemental Table 2). This evidence concerns the gene MKI67 and myeloproliferative disorder.