Meanwhile, statistical differences of infiltrating TME cells between the Asian and white GC patients were investigated; we found that the fractions of B cells naïve, plasma cells, T cells CD8, T cells CD4 memory resting, T cells regulatory, NK cells resting, NK cells activated, monocytes, macrophages M0, and macrophages M2 were significantly increased in AGC, while T cells follicular helper, T cells gamma delta, macrophages M1, dendritic cells resting, dendritic cells activated, mast cells activated, eosinophils, and neutrophils were significantly decreased (Figure 2D). Here, CD4 is linked to gastric cancer.