We identified the aberrant expression status of m6A RNA methylation regulators in MM: RBMX and HNRNPC were significantly upregulated, while METTL3, METTL14, METTL16, ZC3H13, KIAA1429, FTO, and IGF2BP3 were significantly downregulated in MM patients compared to normal plasm samples. The gene discussed is IGF2BP3; the disease is Miyoshi myopathy.