In conclusion, the four m6A regulators (ZC3H13, HNRNPA2B1, HNRNPC, and ZC3H13)-based prognostic risk score can accurately and stably predict the survival of MM patients; and the risk score is tightly associated with the impaired immune infiltration level, which complements current prediction models. The gene discussed is ZC3H13; the disease is Miyoshi myopathy.