The heatmap showed that the expression of nine m6A methylation regulators (FTO, HNRNPC, IGF2BP3, KIAA1429, METTL16, METTL14, METTL3, RBMX, and ZC3H13) were differentially expressed in MM patients compared to normal volunteers (Figure 1A). This evidence concerns the gene METTL16 and Miyoshi myopathy.