Furthermore, KIF15 depletion of C4-2B xenografts in castrated nude mice resulted in delayed tumor progression; the mean tumor volume 463.5 ± 79.92 mm3 in C4-2B shKIF15 xenografts while it was 979 ± 84.57 mm3 in the control group (P = 0.001) (the weight of tumors; shKIF15 vs. control; 0.4633 ± 0.06312 g vs. 1.313 ± 0.09698 g; P < 0.0001) (Figures 2F–H). This evidence concerns the gene KIF15 and neoplasm.