As shown in Figure 1A, KIF15 expression was significantly upregulated in CRPC compared to primary PCa tissues in GSE32269 (32) (P < 0.0001), GSE35988 (33) (P < 0.0001) and GSE74367 (34) (P < 0.0001) datasets. This evidence concerns the gene KIF15 and posterior cortical atrophy.