The factors identified in these studies that contributed to high ICU admissions and high mortality rates were age over 50, presence of infection, leukopenia, thrombocytopenia, high CRP, high liver function tests (LFTs), renal function tests (RFTs), presence of MAS on admission and MAS throughout the hospital stay [16,19,21]. This evidence concerns the gene CRP and Decreased total leukocyte count.