MAP2K4 and colorectal carcinoma: The genotype G/G of the MKK4 rs3826392 variant (-1304T>G) was found in 24.4% (61/250) of the CRC patients and in 35.8% (78/218) of the healthy group; this difference shown statistical significance (OR=0.46; 95% CI=0.26–0.82, P=0.013).