In a mouse model of chronic alcohol-induced hepatic damage, Zhang et al. demonstrated that naringenin treatment could prevent hepatic inflammation, suppress liver fibrosis, and alleviate hepatocyte apoptosis, thus improving the liver function, through decreasing the levels of NF-κB, TGF-β1, and caspase-3, respectively [91]. Here, NFKB1 is linked to Hepatic fibrosis.