THBS1 was upregulated in ESCA (esophageal carcinoma), GBM (glioblastoma multiforme), and PAAD (pancreatic adenocarcinoma) and downregulated in 13 types of cancers, including LUSC (lung squamous cell carcinoma) and KICH (kidney chromophobe). The gene discussed is THBS1; the disease is cancer.