The relationship between methylation and survival showed hypomethylation of THBS1 predicted worse survival in GBM and hypomethylation of THBS5 indicated poorer survival in STAD, which is consistent with the correlation of high expression of THBS1 in GBM or upregulation of THBS5 in STAD with worse survival of the patients (Figure 3(c)). This evidence concerns the gene COMP and glioblastoma.